![]() |
![]() |
IBA Publikation
|
![]() |
epub.oeaw – Institutionelles Repositorium der Österreichischen Akademie der Wissenschaften epub.oeaw – Institutional Repository of the Austrian Academy of Sciences
A-1011 Wien, Dr. Ignaz Seipel-Platz 2
Tel. +43-1-515 81/DW 3420, Fax +43-1-515 81/DW 3400 http://epub.oeaw.ac.at, e-mail: epub@oeaw.ac.at |
![]() |
|
DATUM, UNTERSCHRIFT / DATE, SIGNATURE
BANK AUSTRIA CREDITANSTALT, WIEN (IBAN AT04 1100 0006 2280 0100, BIC BKAUATWW), DEUTSCHE BANK MÜNCHEN (IBAN DE16 7007 0024 0238 8270 00, BIC DEUTDEDBMUC)
|
IBA Publikation, pp. 116-119, 2010/07/16
The function of the immune system declines with age, causing an increased occurrence and severity of infectious diseases and a decreased response to vaccines (Grubeck-Loebenstein et al., 2009). As the thymus gradually loses its ability to replenish the population of naïve T cells, the memory and effector T cells increase in number and dominate the repertoire. The changes in the naïve and memory T cell pool that occur with aging in humans are discussed here, along with a brief update of the knowledge of B cell populations in the elderly.