ITA Nanotrust Dossiers
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DATUM, UNTERSCHRIFT / DATE, SIGNATURE
BANK AUSTRIA CREDITANSTALT, WIEN (IBAN AT04 1100 0006 2280 0100, BIC BKAUATWW), DEUTSCHE BANK MÜNCHEN (IBAN DE16 7007 0024 0238 8270 00, BIC DEUTDEDBMUC)
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ITA Nanotrust Dossiers
Myrtill Simkó
doi:10.1553/ita-nt-028en Eigenverlag/Self
Abstract: Paracelsus postulated that every substance is toxic and that only the dose makes the poison. The question is how to define a certain „dose“ for nanomaterials and for nanoparticles, respectively. Why is it impossible to calculate a distinct dose for nanoparticles? The problem is that nanoparticles are very diverse and heterogeneous regarding their chemical and physical properties. It seems rather unlikely that uniform units of measures or parameters characterizing these properties and reflecting the biological effectiveness could be developed. However, the dose calculation for nanoparticles is of high relevance, especially for risk assessment, limit values regulation and recommendations, respectively. Therefore this dossier outlines the correlation between exposition, dose and dose response and it explains why the knowledge of these crucial points is essential and where the gaps in knowledge still remain. Keywords: nano-dose Published Online: 2012/05/07 08:11:09 Document Date: 2012/04/28 08:10:00 Object Identifier: 0xc1aa5576 0x002af796 Rights: . Das NanoTrust-Team bietet an dieser Stelle in loser Folge sog. Dossiers an, die in leicht-fasslicher, aber wissenschaftlich fundierter Weise auf ca. drei bis sechs Seiten den aktuellen Wissensstand zu den aktuellen Themen der aufkommmenden Nanodebatte zusammenfassen. |
epub.oeaw – Institutionelles Repositorium der Österreichischen Akademie der Wissenschaften epub.oeaw – Institutional Repository of the Austrian Academy of Sciences
A-1011 Wien, Dr. Ignaz Seipel-Platz 2
Tel. +43-1-515 81/DW 3420, Fax +43-1-515 81/DW 3400 http://epub.oeaw.ac.at, e-mail: epub@oeaw.ac.at |