The green nano design principles developed by the German NanoCommission constitute an attempt to establish consensus-based guidelines for environmentally friendly and sustainable production. This initiative fits into the objective of international research and development policy (e.g., Responsible Research and Innovation, RRI) and shall enable to incorporate desired societal aspects into technology developments as soon as possible. The present dossier is concerned with the question to what extent a concept along those lines can contribute to environmentally friendly developments in the area of nanotechnology. For this purpose, it introduces research projects which have implemented certain aspects of the green nano design principles. Moreover, on the basis of technological and scientific research and development, the question is raised whether or not, and if so, to what extent concepts such as green nano design principles can support the incorporation of environmental aspects into research.