Generative Artificial Intelligence (Generative AI) promises to facilitate text creation, explorative research, content analysis and idea generation in policy-oriented TA. However, the question arises to what extent specific quality criteria of policy-oriented TA can still be fulfilled. This article outlines possible fields of application for Generative AI, explores the challenges and prerequisites for application, identifies applicable framework conditions and discusses possible voluntary commitments. Existing guidelines call for traceability and transparency regarding use, but do not address the specific field of application. There is, therefore, an urgent need for an exchange of experience on potential applications of Generative AI in TA practice and the development of recommendations.